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Monday, August 17, 2009

H1N1 influenza prevention and treatment. Oseltamivir's info. :-)

Nauseated this morning.. having bloated stomach, dyspepsia.... argh....

when i read through BNF, i understand it... it's the Side Effects of Oseltamivir. Yes, I'm on prophylaxis dose of Oseltamivir now. Erm.... it's a lot of side effects... Well, i have to monitor the side effects on me, and hope tht i wont lost my renal function by the time i complete it.. haha!! although renal failure is one of the side effects.

okay, Class is on MASK today. yeap.. whole class wearing it except for 2 GANG-HO ppl.. Sher and Tri. muahaha!! both of them really GREAT! anyway, they have enough faith to do that i guess. :-)

Non-Rx quiz is this Friday.. Well, i wish my mates all the best!! :-)



okay, a little bit of knowledge regarding H1N1.
H1N1 is one of the type of Influenza A. Well, the only test to confirm this strain is through Throat Swab which the hospital wont di unless it's a severe case. (FUCK)

It's transmitted through droplets. Tht's why, if a Positive carrier sneezed on the hand, and touched other things, and you happen to tough the place the the person touched.. Eh hem.... u're most likely to get contracted if u dun have the habit of washing ur hand often and with the right way...erm..u'll knw what will happen. :-)

It is air-bourned.. through droplets. tht's why ppl are encouraged to wear a mask everyday, and wash hands often.

Now, Oseltamivir and Zanamivir are the drugs used. Oseltamivir is the first line drug, Zanamivir is the second line because it cannot be used in Asthma patient and those with Respiratory disorder.

Oseltamivir is a drug to treat and prevent Influenza A.
For prevention, it's 1 capsule a day, for 10 days.
For treatment dose, it's 1 capsule twice a day, for 5 days.
(this is only for adult dosing)

Side effects of the drugs are Nausea, dyspepsia, neuropsychiatric disorder, diarrhea...

From BNF 2009:

OSELTAMIVIR

Cautions: renal impairment(Appendix3);pregnancy
(Appendix4);breast-feeding(Appendix5)

Side-effects: nausea,vomiting,abdominal pain,diarrhoea; headache; conjunctivitis; less commonly rash;
also reported,hepatitis,arrhythmias,neuropsychiatric disorders(in children and adolescents), visual disturbances,Stevens-Johnson syndrome,and toxic epidermal necrolysis.


For Dose, refer to doctor if you having any ILI symptoms. ILI-Influenza-Like Illness.

Source: BNF 2009

Till now, the Side Effects varies to individuals. Not all experience the neuropsychiatric side effects.. and minority experienced Nausea, diarrhea... etc etc.

So, this is the info about the drug.


OSELTAMIVIR only works within 48 hours when a person is showing the ILI, for example high fever, cough, sore throat.
those with risk factor, for example pregnancy, hypertension, obesity, asthma, have to be extremely careful if you have ILI,
Get immediate treatment is you have any respiratory distress, for example Shortness Of Breath, Chest Pain,Cough with blood for those who are at high risk (those who have one or more criterion of the risk factor)

Please be responsible to yourself and others. If you are having flu and cough, do not go to the public and spread the disease. Stay at home till the symptoms resolved, and wear a mask wherever you go.

Sleep well, drink at least 3 liters of water per day.. (WHAT?) yes, 3 Liters!! and take vitamin C 500mg once or twice daily as prophylaxis too. :-)

Wash your hands frequently, and those who are exposed to ppl who have ILI, monitor your body temperature everyday. If there's rise of body temperature up to 38 centigrade or more, seek for medical help or advise.

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Avoid public places if possible. :-)


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I'm Glad tht DeEr had settled her PtPtn Loan documents!!! haha!!
All the best to her cuz she has exams this week. :-)
oooh.. thanks to her tht i get to meet my old teachers last Saturday. Skipping class on that day is something meaningful. :-) yeah, i dun feel regret on skipping last Saturday's Endo class.. hehe..
Actually, i only get to knw tht LAst Saturday class is ON after i've promised DeEr to settle the documents for her. So... a promise is a promise. :-)
plus, i think siblings are more important than classes. :-) FAmily first. ;-)



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AL is starting on her new blog. Well, What can i say? it's good to have a blog to express your feelings ... She loves me, i knw. :-) She respects me, i knw :-)

I hope she will find the purpose in her life.. as living is not all about studying. It's more than that. :-)

AL, keep sharing with me. Dun shut your heart towards me. :-)


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Time for Non-Rx. Ciao.

Do you knw tht food which is high in carbohydrate and low in protein can reduce PMS??? haha!! i knew it today!!! :-) as it will increase the Tryptophan level and reduce mood scores. haha! Great! aint it???

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